Scientist, Antibody Engineering
Scientist, Antibody Engineering
Scientist, Antibody Engineering
Chai Discovery
Chai Discovery is seeking an Antibody Engineer to contribute to the development of biologics using advanced AI models. The role involves designing constructs, running expression and purification campaigns, and developing assays for antibody discovery, with a focus on real-world therapeutic applications.
Qualification
- PhD or equivalent work experience in Biological Sciences, Protein Engineering, Biochemistry, or a related field.
- Hands-on expertise in design and characterization of antibody-based biologics.
- Experience with advanced modalities such as bispecifics, TCEs, or ADCs is a plus.
- Proficient in molecular-biology workflows including cloning, expression, purification, and quality control.
- Familiarity with binding and developability assays such as SPR/BLI, ELISA, and flow cytometry.
Responsibility
- Design constructs for monoclonals, bispecifics, TCEs, engineered cytokines, multifunctionals, and ADC/DAC formats.
- Run expression and purification campaigns for antibody-based biologics.
- Develop fit-for-purpose assays to evaluate affinity, specificity, and developability.
- Generate data that feeds into the model-training loop for AI drug design.
- Collaborate with computational teams to communicate experimental results and insights.
